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Fertility Preservation Options


Preserving reproductive options BEFORE and DURING cancer treatments

Many current fertility preservation techniques require Controlled Ovarian Stimulation (COS) prior to oocyte or embryo banking.  Important information about COS includes:Early referral to a fertility specialist is important
Controlled Ovarian Stimulation (COS) – General Information

  • Pre-cycle considerations
  • Medications
  • General protocol information
  • Cryopreservation strategies
  • Additional Considerations for COS in cancer patients


  • Is COS safe in women with cancer?
  • Is COS safe in women with hormone-sensitive cancers?

Protocol challenges

  • Which exact stimulation protocol is best?
  • How can we rapidly induce a menstrual cycle?
  • Are IVF cycles different for women with cancer?
  • Can a patient undergo COS after receiving chemotherapy?

Chance of pregnancy after embryo cryopreservation

  • Considerations
  • Can we give a blanket estimation of future pregnancies?
  • Society for Reproductive Technology (SART) Database

Chance of pregnancy after oocyte cryopreservation

Fertility preservation options are also available that do not require hormonal stimulation:

Reproductive options AFTER cancer

Pregnancy Rates After Cancer
Several factors need to be accounted for when predicting the change of future pregnancy when banking embryos or eggs. First of all, one must consider the anticipated ‘success’ of a controlled ovarian stimulation (COS) procedure, in terms of stimulation characteristics, oocyte yield, fertilization rates, etc. Next, it is important to predict actual pregnancy rates from cryopreserved oocytes or embryos per transfer cycle.Assessing ovarian reserve

  • What does the literature tell us?
  • Childhood cancer survivor study
  • Models to predict premature menopause
  • What does the presence or absence of menses indicate?


When and how should a frozen embryo transfer occur?

  • When is it safe to consider pregnancy?
  • What protocol is best for frozen embryo transfers in women with hormone-sensitive cancers?

Logistics and safety of pregnancy after cancer

  • Safety of pregnancy:  recurrence risk
  • Safety of pregnancy:  offspring
  • Timing of pregnancy


The information provided on the CKN website is designed to support, not replace, the relationship that exists between a patient and his/her physician.  CKN thanks the Oncofertility Consortium and Save My Fertility for providing content on this page. If you’d like more information, or to make a suggestion: Contact us.

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