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Tag Archives: goserelin

Goserelin in Fertility Preservation

Rachel Adilmanby Rachel Adilman, BSc

 

One of the most commonly used chemotherapy drugs, cyclophosphamide, can lead to ovarian failure and loss of fertility, a tragic consequence of cancer treatment that has led researchers world-wide in search of a solution.  The risk of chemotherapy to induce premature menopause is well-documented, and depends largely on the patient’s age, as well as the type and dose of chemotherapy.  The risk of premature menopause (i.e. permanent amenorrhea) following cytotoxic chemotherapy is 50% in women aged 35-50, and as high as 85% in women over the age of 40 [Wong et al., 2012].

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