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Tag Archives: leukemia

Childhood ALL: Increased Survival Leads to a Greater Emphasis on Preserving Neurocognitive Function

GregoryAuneby Gregory Aune, MD, PhD, CKN Editor

 

Childhood Cancer Survivors have their own unique set of issues that often go unaddressed by health care professionals once treatment has ended and the child enters adulthood.  Although the last 20 years have seen growth in survivorship research, this research is rarely filtered down to the people who need it most – the survivors and their families.  Dr. Gregory Aune, Pediatric Oncologist, researcher, childhood cancer survivor and advocate, has taken on the position of CKN Editor, Knowledge Translation – Childhood Cancer Survivorship.  His goal is simple:  to help empower childhood cancer survivors to start a dialogue with their doctors by publishing short, easy-to-read research study summaries, like this one.

 


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New Biomarker Predicts Late Neurocognitive Deficits in Adult Survivors of Childhood Leukemia

GregoryAuneby Gregory Aune, MD, PhD, CKN Editor

 

Childhood Cancer Survivors have their own unique set of issues that often go unaddressed by health care professionals once treatment has ended and the child enters adulthood.  Although the last 20 years have seen growth in survivorship research, this research is rarely filtered down to the people who need it most – the survivors and their families.  Dr. Gregory Aune, Pediatric Oncologist, researcher, childhood cancer survivor and advocate, has taken on the position of CKN Editor, Knowledge Translation – Childhood Cancer Survivorship.  His goal is simple:  to help empower childhood cancer survivors to start a dialogue with their doctors by publishing short, easy-to-read research study summaries, like this one.

 


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Neurocognitive Function, Sleep, and Fatigue in Female Childhood ALL Survivors

GregoryAuneby Gregory Aune, MD, PhD, CKN Editor

 

Childhood Cancer Survivors have their own unique set of issues that often go unaddressed by health care professionals once treatment has ended and the child enters adulthood.  Although the last 20 years have seen growth in survivorship research, this research is rarely filtered down to the people who need it most – the survivors and their families.  Dr. Gregory Aune, Pediatric Oncologist, researcher, childhood cancer survivor and advocate, has taken on the position of CKN Editor, Knowledge Translation – Childhood Cancer Survivorship.  His goal is simple:  to help empower childhood cancer survivors to start a dialogue with their doctors by publishing short, easy-to-read research study summaries, like this one.

 


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Surviving Survivorship

Clarissaby Clarissa Schilstra, Living with Cancer

 

A College Student and 2X Leukemia Survivor’s Perspective

 

I was diagnosed with acute lymphoblastic leukemia (ALL) for the first time at 2 ½ years old, and went through 2 ½ years of treatment.  I then relapsed when I was 13, at which point I went through another 2 ½ years of more intensive chemotherapy and radiation treatment.

 

When I finished my relapse treatment, at the age of 15, I felt liberated.  I had finally conquered the disease that had taken over such a significant portion of my childhood.  Little did I know, navigating survivorship would present a whole new kind of challenge.

 

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Top 10 Parenting Tips: Childhood Cancer + Down Syndrome

BeckyCareyby Becky Carey, Caregiver

As a mom to a daughter with Down syndrome, I became accustomed to life in a clinic setting early on.  When my daughter was just four weeks old, she had been to her first genetic specialist, specialty developmental pediatrician, and speech therapist.  During that time we had also lined up appointments for her to see a cardiologist, audiologist as well as other therapy services.  Not at all what I was expecting when I became a new mom; but we adjusted well, and we were very thankful for her overall good health.

 

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Chronic lymphocytic leukemia and breast cancer as synchronous primary in a male— a rare combination

A Resident Education Article

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Case Study

by Biswajit Dubashi, MD, DM

A 69-year-old man with no comorbidities and a family history of cancer presented with a right breast lump of 1 month’s duration. On examination, a 3×2-cm right breast lump with ulceration, fixed to the pectoralis major muscle, was noted. A right axillary hard mobile lymph node was also found. Investigations revealed hemoglobin 8.2 g/dL and total leucocytes 63×109/L, with a differential count of neutrophils 13%, lymphocytes 2%, abnormal cells 85%, and platelets 75×109/L. Bone marrow aspiration and biopsy revealed cll with CD5+ and CD23+. Trucut biopsy from the breast lump revealed an infiltrating ductal carcinoma positive for the estrogen receptor and negative for the progesterone receptor. Staging work-up was normal. The patient had renal dysfunction (creatinine clearance: 30 mL/min) with 13% elevation in uric acid and normal serum calcium and potassium, suggestive of tumour lysis syndrome. The final diagnosis was synchronous primary with carcinoma right breast T4bN1M0 and cll Rai stage iv.

 

Questions:

  1. What are the Malignancies associated with Chronic Lymphocytic Lymphoma?
  2. What are the various theories associated with development of second malignancies in patients?
  3. Which malignancy will you treat initially?
  4. Outline the management of breast cancer in the above patient.
  5. Outline the management of cll in the above patient.

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