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Tag Archives: medulloblastoma

Novel subgroups for clinical classification & outcome prediction in childhood medulloblastoma

by Edward C Schwalbe, Janet C Lindsey, Sirintra Nakjang, Stephen Crosier, Amanda J Smith, Debbie Hicks, Gholamreza Rafiee, Rebecca M Hill, Alice Iliasova, Thomas Stone, Barry Pizer, Antony Michalski, Abhijit Joshi, Stephen B Wharton, Thomas S Jacques, Simon Bailey, Daniel Williamson, Steven C Clifford.


Originally published in The Lancet Oncology, May 22nd 2017


Medulloblastoma, the most common CNS tumor of childhood, is the leading cause of cancer deaths in young people. What was once thought of as a single disease is, since an International consensus meeting in 2012, now recognized as four distinct molecular entities (WNT, SHH, Grp3, Grp4), each defined by differing disease features and outcomes. However, the studies that defined this consensus were based on small cohorts of tumors, and were performed using low-resolution approaches.


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New Studies Give Hope to Children with Brain Tumours: Evie’s Story


New Research Gives Hope to Children with Most Common Types of Brain Tumours

by Sue McKechnie, CKN Childhood Cancer Advocacy Co-Editor

Evie was diagnosed with a brain tumour when she was 6 months old.  After 3 straight years of chemotherapy, her tumour looked stable enough to stop treatment.  After being treatment free for 17 months, an MRI showed that her tumour was growing.

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