|Harvesting eggs, IVF, and freezing of embryos for later implantation||Before or after treatment||10-14 days from menses; outpatient surgical procedure||Need partner or donor sperm|
|Use of shielding to reduce scatter radiation to the ovaries||During treatment||In conjunction with radiation treatments||Does not protect against effects of chemotherapy|
|Surgical repositioning of ovaries away from the radiation field||Before treatment||Outpatient procedure or in conjunction with gynecologic cancer surgery|
|Surgical removal of the cervix with preservation of the uterus||During treatment||Inpatient surgical procedure||Limited to early stage cervical cancer|
Egg Banking (Experimental)
|Harvesting and freezing of unfertilized eggs for IVF and implantation after cancer treatment||Before or after treatment||10-14 days from menses; outpatient surgical procedure||May be attractive to single women or those opposed to embryo creation|
Ovarian Tissue Banking (Experimental)
|Freezing of ovarian tissue and reimplantation of tissue or in vitro maturation of follicles and fertilization of eggs after cancer treatment||Before or after treatment||Outpatient surgical procedure||Tissue not suitable for transplant if high risk of ovarian metastases; no live births to date from in vitro maturation|
Ovarian Suppression (Experimental)
|GnRH analogs or antagonists used to suppress ovaries||During treatment||In conjunction with chemotherapy||Does not protect from radiation effects|
Table adapted from SaveMyFertility.org (2011).
The information provided on the CKN website is designed to support, not replace, the relationship that exists between a patient and his/her physician. CKN thanks the Oncofertility Consortium for providing content on this site. If you’d like more information, or to make a suggestion: Contact us.
Preserving reproductive options BEFORE and DURING cancer treatments
|Many current fertility preservation techniques require Controlled Ovarian Stimulation (COS) prior to oocyte or embryo banking. Important information about COS includes:Early referral to a fertility specialist is important|
Controlled Ovarian Stimulation (COS) – General Information
- Pre-cycle considerations
- General protocol information
- Cryopreservation strategies
- Additional Considerations for COS in cancer patients
- Is COS safe in women with cancer?
- Is COS safe in women with hormone-sensitive cancers?
- Which exact stimulation protocol is best?
- How can we rapidly induce a menstrual cycle?
- Are IVF cycles different for women with cancer?
- Can a patient undergo COS after receiving chemotherapy?
Chance of pregnancy after embryo cryopreservation
- Can we give a blanket estimation of future pregnancies?
- Society for Reproductive Technology (SART) Database
Chance of pregnancy after oocyte cryopreservation
Fertility preservation options are also available that do not require hormonal stimulation:
Reproductive options AFTER cancer
|Pregnancy Rates After Cancer|
Several factors need to be accounted for when predicting the change of future pregnancy when banking embryos or eggs. First of all, one must consider the anticipated ‘success’ of a controlled ovarian stimulation (COS) procedure, in terms of stimulation characteristics, oocyte yield, fertilization rates, etc. Next, it is important to predict actual pregnancy rates from cryopreserved oocytes or embryos per transfer cycle.Assessing ovarian reserve
- What does the literature tell us?
- Childhood cancer survivor study
- Models to predict premature menopause
- What does the presence or absence of menses indicate?
When and how should a frozen embryo transfer occur?
- When is it safe to consider pregnancy?
- What protocol is best for frozen embryo transfers in women with hormone-sensitive cancers?
Logistics and safety of pregnancy after cancer
- Safety of pregnancy: recurrence risk
- Safety of pregnancy: offspring
- Timing of pregnancy
The information provided on the CKN website is designed to support, not replace, the relationship that exists between a patient and his/her physician. CKN thanks the Oncofertility Consortium and Save My Fertility for providing content on this page. If you’d like more information, or to make a suggestion: Contact us.
click on the chart to view
The information provided on the CKN website is designed to support, not replace, the relationship that exists between a patient and his/her physician. CKN thanks the Oncofertility Consortiumfor providing content on this site. If you’d like more information, or to make a suggestion: Contact us.