Recently I had the honor of speaking at the FACTOR Osteosarcoma Conference in Miami, FL, put on by the nonprofit MIB Agents. This was the first osteosarcoma conference of its type. For two days, sitting in an ornate and impressively handcrafted room at the Biltmore Hotel in Coral Gables, FL, 150+ researchers, clinicians, parents, patients and advocates breathed in the same air. Throughout the conference, there were medical presentations involving surgical intervention, limb salvage, drug discovery, drug development, trial design, genetics, patient advocacy and much more. The agenda was amazingly and stressfully jam-packed. The purpose of the two day meeting was to bring stakeholders together in one room and discuss priorities for the osteosarcoma community. The talk I gave was affectionately titled, “Guilty as Charged: Opportunities from Miami and Beyond.” I was guilty of providing Ann Graham, from MIB Agents, and Theresa Beech, an osteosarcoma parent herself and a childhood cancer community outlier (think Malcolm Gladwell’s book Outliers), with the thought that if they wanted to see change for the osteosarcoma community, then they should think about having a conference. And thus, welcome to Miami circa February 2017.