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Tag Archives: Radiation therapy

Decreased Therapy Results in Fewer Second Cancers

GregoryAuneby Gregory Aune, MD, PhD, CKN Editor


Childhood Cancer Survivors have their own unique set of issues that often go unaddressed by health care professionals once treatment has ended and the child enters adulthood.  Although the last 20 years have seen growth in survivorship research, this research is rarely filtered down to the people who need it most – the survivors and their families.  Dr. Gregory Aune, Pediatric Oncologist, researcher, childhood cancer survivor and advocate, has taken on the position of CKN Editor, Knowledge Translation – Childhood Cancer Survivorship.  His goal is simple:  to help empower childhood cancer survivors to start a dialogue with their doctors by publishing short, easy-to-read research study summaries, like this one.


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Post-operative Concurrent Chemotherapy and Radiation Therapy for High Risk Squamous Cell Carcinoma of the Head and Neck: Review of RTOG 9501

by Jonathan Klein, MD

Surgery plus adjuvant radiotherapy had long been the standard treatment for patients with squamous cell carcinoma of the head and neck. Looking at the results for all patients undergoing this regimen, local/regional recurrence rates were around 30%, distant metastases developed in 25% and 5-year survival was around 40%. However, in patients with high risk features such as extracapsular extension, positive surgical margins and others, recurrence rates of up to 61% had been observed and 5 year survival dipped to around 30%.1

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